化學(xué)配方數(shù)據(jù)庫(kù)
| 配方類型： |
DRUGS |
| 配方說(shuō)明： |
Rapidly Disintegrating Coatings for Pills (Colored) |
| 配方組成： |
Dry Lacquer Substance Content/5%
Lacquer Dispersio
Hydroxypropyl Methylcellulose/10
Talc/Magnesium Stearate/159
Polyethylene Glycol 6000/30
Antifoam Agent/1
Titanium Dioxide/Color Pigment/100
"Eudragit" E 30 D/333
Water/700
Water/667
Solids Content/20% |
| 配制方法： |
To produce the pigment suspension, water is measured out and the solids are added and stirred in. Hydroxypropyl methylcellulose (e.g., "Methocel" E5) is dissolved in water beforehand to produce a 10% solution and is then added, followed by the polyethylene glycol 6000 as a 33% aqueous solution. Next the whole pigment suspension is finely dispersed, using a suitable dispersion system (toothed colloid mills, corundum disc mills, ball mills), and is poured into the diluted "Eudragit" E 30 d dispersion, but only immediately prior to use. The mixture should be processed within one to two days. |
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